Table 2.
Patients
| N = 534 | |
|---|---|
| Demographics | |
| Age, Median (IQR) | 6.0 (3.0, 12.0) |
| Sex (male), N (%) | 281 (52.6) |
| Race, N (%) | |
| White | 354 (66.3) |
| Black | 68 (12.7) |
| Asian | 17 (3.2) |
| Other | 95 (17.8) |
| Medicaid insurance, N (%) | 214 (40.1) |
| Hospital Region, N (%) | |
| Northeast | 92 (17.2) |
| Southeast | 90 (16.9) |
| Southwest | 60 (11.2) |
| Midwest | 156 (29.2) |
| West | 136 (25.5) |
| Clinical Features and Medication Exposures | |
| Length of stay in days, Median (IQR) | 6.0 (4.0, 9.0) |
| ICU level of care, N (%) | 42 (7.9) |
| Macrophage activation syndrome*, N (%) | 63 (11.8) |
| Glucocorticoids, N (%) | 309 (57.9) |
| Biologics^, N (%) | 156 (29.2) |
| Anakinra, N (%) | 137 (25.7) |
| Canakinumab, N (%) | 11 (2.1) |
| Tocilizumab, N (%) | 20 (3.7) |
| Methotrexate, N (%) | 41 (7.7) |
| Scheduled NSAIDs, N (%) | 452 (84.6) |
| Readmission ≤ 90 days after discharge#, N (%) | 75 (14.0) |
Based on discharge ICD CM code. Diagnosis of MAS may have occurred at any point during hospitalization.
Not mutually exclusive. 9 patients received both canakinumab and anakinra and 3 patients received both anakinra and tocilizumab during hospitalization.
All-cause readmissions.