Table 2.
Oxidative stress markers in follicular fluid and serum of PCOS subjects and controls
| Controls (n = 60) | PCOS (n = 86) | P value | P* adjusted | |
|---|---|---|---|---|
| Oxidative stress levels of FF | ||||
| TOC (μM H2O2) | 7.03 ± 2.45 | 10.13 ± 2.68 | <0.001 | <0.001 |
| TAC (μM) | 1.15 ± 0.27 | 1.18 ± 0.28 | 0.724 | 0.953 |
| OSI | 6.50 ± 2.91 | 9.44 ± 4.28 | <0.001 | 0.004 |
| MDA (μM) | 4.81 ± 3.08 | 4.93 ± 2.60 | 0.822 | 0.132 |
| GSH (μM) | 2.43 ± 0.83 | 2.49 ± 0.98 | 0.692 | 0.72 |
| SOD (U/mL) | 37.31 ± 9.06 | 40.30 ± 8.52 | 0.093 | 0.626 |
| Oxidative stress levels of serum | ||||
| TOC (μM H2O2) | 8.82 ± 2.57 | 11.76 ± 2.92 | <0.001 | 0.003 |
| TAC (μM) | 0.65 ± 0.11 | 0.65 ± 0.11 | 0.873 | 0.512 |
| OSI | 15.63 ± 3.70 | 18.39 ± 4.74 | <0.001 | 0.001 |
| MDA (μM) | 5.96 ± 2.84 | 8.04 ± 2.50 | <0.001 | 0.18 |
| GSH (μM) | 1.57 ± 0.35 | 1.63 ± 0.40 | 0.339 | 0.555 |
| SOD (U/mL) | 32.70 ± 6.75 | 32.38 ± 6.94 | 0.811 | 0.599 |
TOC total oxidant capacity, TAC total antioxidant capacity, OSI oxidative stress index, MDA malonaldehyde, GSH glutathione, SOD superoxide dismutase
Values are presented as the mean ± SD
P* adjusted: BMI, HOMA-IR, and LH/FSH are adjusted as covariants