Table 1.
Summary of reports according to distinguished aspects of ART
| Category | Type of fluid | Evaluated with | Result(s) | Reference(s) |
|---|---|---|---|---|
| Male | Semen | Parameters | Correlated with sperms’ viability, motility, morphology, and capacitation index | [22, 25] |
| Not correlated with SDF | [26] | |||
| Disorder(s) | Correlated with azoospermia, oligo-, astheno-, and oligoasthenoterato-zoospermia | [16, 23] | ||
| ART outcome | Correlated with sperm retrieval chance in NOA patients | [28] | ||
| Not correlated with embryo quality and pregnancy | [26] | |||
| Genetic | Correlated with microdeletions (AZFa, AZFb, and AZFc) | [23] | ||
| Epigenetic | Correlated with testis and epididymis-specific promoters | [28] | ||
| Female | Serum | Disorder(s) | Correlated with subfertility | [36] |
| Not correlated with PCOS and endometriosis | [32, 33] | |||
| Epigenetic | Not correlated | [32] | ||
| ART outcome | Controversial results regarding pregnancy | [31, 34, 35] | ||
| Follicular fluid | Disorder(s) | Correlated with endometriosis and poor ovarian reserve, but controversialresults for PCOS | [33, 39, 43] | |
| ART outcome | Not correlated with fertilization rate | [40, 42] | ||
| Correlated with embryo quality, except one study | [38–45] | |||
| Correlated with pregnancy, except one study | [33, 38, 39, 43–45] | |||
| Embryo | SCM | ART outcome | Correlated with embryo quality | [15, 54, 55] |
| Genetic disorder | Correlated with X-link disorder, thalassemia, MTHFR C677T polymorphism,and cystic fibrosis | [52, 59–62] | ||
| Aneuploidy | Distinguished concordance rates with regarded TE/whole embryo (from 56.3to > 95%) | [63, 66, 67, 69, 75, 76] | ||
| BF | ART outcome | Correlated with embryo quality | [58] | |
| Aneuploidy | Distinguished concordance rates with regarded TE/whole embryo (from 33.3to 97.4%) | [50, 51, 77–80] | ||
| SCM-BF | Aneuploidy | Distinguished concordance rates with regarded TE/whole embryo (from 87.5to 97.8%) | [52, 53, 82, 83, 85] |