Table 7.
Statistical comparison of primary analysis with a consecutive secondary analysis, in which four patients were excluded because of normal PET results that changed the clinical diagnosis from IPS to Non-PS
| Primary analysis (43 patients) | Secondary analysis (39 patients) | |||
|---|---|---|---|---|
| Imaging modality | 6-[18F]FDOPA PET | N1 (%) | 6-[18F]FDOPA PET | N1 (%) |
| Sensitivity | 92.6% | 81.5 | 92.6% | 81.5 |
| Specificity | 93.8% | 75.0 | 91.7% | 75.0 |
| Positive predictive value | 96.2% | 84.6 | 96.2% | 88.0 |
| Negative predictive value | 88.2% | 70.6 | 84.6% | 64.3 |
| Accuracy | 93.0% | 79.1 | 92.3% | 79.5 |
| Kappa (all patients) | 0.611 (p < 0.001) | 0.604 (p < 0.001) | ||