Table 2.
Main effect of group on vmPFC resting-state connectivity
| Region | BA | Size | x | y | z | Peak Z-score |
|---|---|---|---|---|---|---|
| Obese > lean participants at T0 | ||||||
| Cerebellum | 729 | −20 | −80 | −44 | 5.30 | |
| 848 | 14 | −78 | −44 | 4.95 | ||
| dlPFC | 47 | 166 | −34 | 10 | 46 | 4.26 |
| Obese < lean participants at T0 | ||||||
| Ventral striatum | 172 | −10 | 10 | −4 | 4.51 | |
| Hippocampus | 283 | 22 | −48 | 8 | 4.44 | |
| Obese > lean participants at T8 | ||||||
| IFG | 45/46/47 | 243 | −54 | 38 | 12 | 4.74 |
| vlPFC | 47/11 | 191 | 44 | 42 | −12 | 4.15 |
| 10/11 | 228 | 30 | 60 | 0 | 4.08 | |
The peak co-ordinates and Z-score values are listed for lean participants compared to obese patients before at T0 and on average 8 months after bariatric surgery at T8. All peaks surpassed a voxel-wise threshold of PFDR < 0.05 FDR corrected on the cluster level. The xyz coordinates correspond to the Montreal Neurological Institute (MNI) space.
Abbreviations: dlPFC, dorsolateral prefrontal cortex; IFG, inferior frontal gyrus; vlPFC, ventrolateral prefrontal cortex.