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. 2021 Feb 2;8:594283. doi: 10.3389/fcell.2020.594283

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Copyright © 2021 Liu, Chen, Lin, Xiang, Yang, Zheng, Xiong and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experiment paradigm. (A) In vivo cohort for MCAO model of ischemic stroke in mice. The drugs were administrated into left ventricles 24 h before MCAO. (B) In vitro cohort for OGD/R experiment in primary mouse astrocytes. After 12 h pre-incubation of drugs, OGD/R was developed in cultured astrocytes.