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. 2021 Feb 2;12:590633. doi: 10.3389/fgene.2021.590633

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Copyright © 2021 Li, Jin, Sun, Wu, Hu and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Overexpression of circ_0065149 promoted the viability of HUVECs treated with ox-LDL. (A) Expression of circ_0065149 in HUVECs was measured by qRT-PCR. *P < 0.05 vs. the Control group. (B) Expression of circ_0065149 in HUVECs transfected with Vector or OE circ_0065149. *P < 0.05 vs. the Vector group. (C) LDH leakage was detected using an LDH Cytotoxicity Assay Kit. *P < 0.05, ox-LDL + Vector vs. the Con-Vector group; ox-LDL + OE Circ vs. the ox-LDL + Vector group. (D) Cell viability was measured by a CCK-8 assay. *P < 0.05, ox-LDL + Vector vs. the Con-Vector group; ox-LDL + OE Circ vs. the ox-LDL + Vector group. Data are shown as means ± SD.