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. 2021 Feb 15;11:3814. doi: 10.1038/s41598-021-83432-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Stroke decreased acute voluntary movement in open field behavioral test. Representative 10-min movement tracings shown for non-stroked (black) and MCAO (red) pigs across all time points (a). At 2d post-MCAO, MCAO pigs had decreased distance traveled (b), movement duration (c), and average velocity (d) compared to non-stroked pigs. No significant differences were observed at 8d, 15d, and 27d post-MCAO in both groups (p > 0.05). # and ## indicated statistically different between groups.