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. 2021 Feb 2;10:572097. doi: 10.3389/fonc.2020.572097

Table 2.

Organ uptake, tumor uptake, tumor/blood ratio and tumor/muscle ratio of Al18F-NOTA-NI and 18F-MISO.

Organ (Mean ± SD, %ID/g) 20 min 60 min 120 min
Al18F-NOTA-NI 18F-MISO p-value Al18F-NOTA-NI 18F-MISO p-value Al18F-NOTA-NI 18F-MISO p-value
Liver 5.24 ± 0.54 9.16 ± 0.16 <0.001* 4.76 ± 0.78 6.08 ± 0.76 0.104 3.90 ± 0.55 5.74 ± 0.33 0.008*
Intestine 2.67 ± 0.37 2.67 ± 0.37 0.002* 1.91 ± 0.40 1.91 ± 0.40 0.114 2.21 ± 0.65 2.41 ± 0.10 0.648
Liver+ Intestine 7.91 ± 0.84 15.16 ± 0.57 <0.001* 6.67 ± 1.02 9.21 ± 0.74 0.025* 6.11 ± 0.98 8.14 ± 0.30 0.026*
Kidney 17.90 ± 0.81 7.49 ± 0.17 <0.001* 6.75 ± 1.31 3.29 ± 0.81 0.018* 4.50 ± 0.89 2.57 ± 0.16 0.060
Blood 7.38 ± 0.14 5.94 ± 1.24 0.180 1.53 ± 0.03 1.58 ± 0.31 0.811 1.01 ± 0.44 1.30 ± 0.21 0.361
Muscle 2.71 ± 0.18 6.03 ± 0.72 0.011* 1.13 ± 0.03 2.04 ± 0.37 0.013* 0.81 ± 0.11 1.40 ± 0.45 0.088
Tumor 3.61 ± 0.22 4.45 ± 0.56 0.072 2.51 ± 0.99 2.78 ± 0.56 0.705 2.16 ± 0.24 2.26 ± 0.94 0.862
Tumor/Blood Ratio 0.49 ± 0.03 0.76 ± 0.05 0.002* 1.63 ± 0.51 1.76 ± 0.12 0.743 2.32 ± 0.53 1.70 ± 0.39 0.253
Tumor/Muscle Ratio 1.33 ± 0.10 0.74 ± 0.01 0.013* 2.21 ± 0.70 1.37 ± 0.16 0.174 2.67 ± 0.08 1.58 ± 0.24 0.004*

*p < 0.05.