TABLE 1.
List of top 20 candidate genes identified by TWAS for AMI.
| Gene | Chromosome | Best GWAS ID | TWAS P-value | Comparative tissue |
| SURF2 | 9 | rs495828 | 1.25 × 10–12 | Heart left ventricle |
| RP11-378J18.8 | 1 | rs17163358 | 8.33 × 10–11 | Heart left ventricle |
| PSRC1 | 1 | rs7528419 | 1.18 × 10–10 | Whole blood |
| CARF | 2 | rs6722332 | 2.41 × 10–10 | Whole blood |
| RP11-378J18.8 | 1 | rs17163358 | 4.83 × 10–9 | Whole blood |
| GGCX | 2 | rs1561198 | 1.01 × 10–8 | Whole blood |
| POC1B | 12 | rs2681472 | 1.07 × 10–8 | Whole blood |
| IL6R | 1 | rs4845618 | 7.09 × 10–8 | Whole blood |
| SH2B3 | 12 | rs653178 | 9.54 × 10–8 | Whole blood |
| FAM177B | 1 | rs17163358 | 1.36 × 10–7 | Whole blood |
| TAF1A | 1 | rs17163358 | 1.39 × 10–7 | Whole blood |
| ABO | 9 | rs495828 | 1.70 × 10–7 | Heart left ventricle |
| ICA1L | 2 | rs6722332 | 1.78 × 10–7 | Heart left ventricle |
| MIA3 | 1 | rs17163358 | 2.33 × 10–7 | Heart left ventricle |
| BSND | 1 | rs11591147 | 2.52 × 10–7 | Whole blood |
| KIAA1462 | 10 | rs2505083 | 2.60 × 10–7 | Heart left ventricle |
| UBE2Q1 | 1 | rs4845618 | 5.30 × 10–7 | Whole blood |
| RP11-422P24.10 | 1 | rs4845618 | 6.23 × 10–7 | Whole blood |
| CDKN2A | 9 | rs4977574 | 7.47 × 10–7 | Whole blood |
| SRD5A3-AS1 | 4 | rs11945371 | 9.05 × 10–7 | Whole blood |