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. 2021 Feb 15;7:4. doi: 10.1038/s41526-021-00132-0

Table 2.

Erythropoietic markers. Data (95% CI) for erythropoietic markers before, during, and after bed rest.

Measure Bed rest study timepoint
BDC-4 HDT20 HDT49 HDT60 R1 R7 R13 R30
RBC 106/mm3 4.529 (4.393–4.665) 5.011 (4.887–5.134) 5.007 (4.834–5.179) 4.803 (4.627–4.979) 4.469 (4.322–4.615) 4.348 (4.180–4.516) 4.358 (4.168–4.547)**
Reticulocyte 103/µl 47.4 (39.1–55.6) 50.7 (41.2–60.3) 45.9 (38.9–52.9) 63.9 (55.9 – 71.9) 56.6 (48.6–64.6)**
tHb g/kg 10.9 (10.4–11.5)** 10.0 (9.5–10.5)** 9.6 (9.1–10.1)**
tHb g 818.2 (764.4–872.0)** 735.0 (673.9–796.0)** 723.5 (674.6–772.5)**
Hb g/dl 13.7 (13.4–14.0) 15.1 (14.8–15.4) 15.0 (14.6–15.5) 14.4 (13.9–14.8) 13.4 (13.0–13.8) 13.1 (12.7–13.5) 13.2 (12.7–13.6)
Participants Hb < 13.0 g/dl 2/20 0/20 0//20 0/20 5/20 9/20 7/17
EPO mUI/ml 12.2 (10.2–14.2) 8.9 (7.7–10.1) 10.1 (8.7–11.6) 16.3 (12.8 – 19.9) 17.8 (13.6–22.0)**
Haptoglobin g/l 1.03 (0.89–1.16) 0.99 (0.87–1.12) 1.04 (0.89–1.19) 1.07 (0.94–1.21) 1.10 (0.93–1.27)**

Underlined values show the bed rest phase. Bold data were statistically significant from baseline (p < 0.05). **n = 17.