Table 2.
Erythropoietic markers. Data (95% CI) for erythropoietic markers before, during, and after bed rest.
Measure | Bed rest study timepoint | |||||||
---|---|---|---|---|---|---|---|---|
BDC-4 | HDT20 | HDT49 | HDT60 | R1 | R7 | R13 | R30 | |
RBC 106/mm3 | 4.529 (4.393–4.665) | 5.011 (4.887–5.134) | 5.007 (4.834–5.179) | 4.803 (4.627–4.979) | 4.469 (4.322–4.615) | 4.348 (4.180–4.516) | 4.358 (4.168–4.547)** | |
Reticulocyte 103/µl | 47.4 (39.1–55.6) | 50.7 (41.2–60.3) | 45.9 (38.9–52.9) | 63.9 (55.9 – 71.9) | 56.6 (48.6–64.6)** | |||
tHb g/kg | 10.9 (10.4–11.5)** | 10.0 (9.5–10.5)** | 9.6 (9.1–10.1)** | |||||
tHb g | 818.2 (764.4–872.0)** | 735.0 (673.9–796.0)** | 723.5 (674.6–772.5)** | |||||
Hb g/dl | 13.7 (13.4–14.0) | 15.1 (14.8–15.4) | 15.0 (14.6–15.5) | 14.4 (13.9–14.8) | 13.4 (13.0–13.8) | 13.1 (12.7–13.5) | 13.2 (12.7–13.6) | |
Participants Hb < 13.0 g/dl | 2/20 | 0/20 | 0//20 | 0/20 | 5/20 | 9/20 | 7/17 | |
EPO mUI/ml | 12.2 (10.2–14.2) | 8.9 (7.7–10.1) | 10.1 (8.7–11.6) | 16.3 (12.8 – 19.9) | 17.8 (13.6–22.0)** | |||
Haptoglobin g/l | 1.03 (0.89–1.16) | 0.99 (0.87–1.12) | 1.04 (0.89–1.19) | 1.07 (0.94–1.21) | 1.10 (0.93–1.27)** |
Underlined values show the bed rest phase. Bold data were statistically significant from baseline (p < 0.05). **n = 17.