Table 1.
Characteristics and source of genome-derived proteomes of kinetoplastids used in this work.
| Species name | Life cycle | Genome source | Protein sequence source1 | Publication | Genome size (Mb) | Number of sequences2 |
|---|---|---|---|---|---|---|
| Angomonas deanei | Endosymbiont-bearing monoxenous | NCBI | Orf/blastx REFSEQ | PMID23560078 | 23 | 6255 |
| Angomonas desouzai | Endosymbiont-bearing monoxenous | NCBI | Orf/blastx REFSEQ | PMID21420905 | 24.3 | 6282 |
| Blechomonas ayalai | Monoxenous | TriTrypdb | TriTrypdb | PMID27021793 | N/A | 8037 |
| Bodo saltans | Free living | NCBI | NCBI | PMID19068121 | 39.9 | 17,840 |
| Crithidia acanthocephali | Monoxenous | NCBI | Orf/blastx REFSEQ | PMID23560078 | 33.8 | 11,800 |
| Crithidia bombi | Monoxenous | NCBI | Orf/blastx REFSEQ | PMID29304093 | 31.4 | 7675 |
| Crithidia expoeki | Monoxenous | NCBI | Orf/blastx REFSEQ | PMID29304093 | 34 | 10,254 |
| Crithidia mellificae | Monoxenous | NCBI | Orf/blastx REFSEQ | PMID24743507 | 58.7 | 7660 |
| Crithidia fasciculata | Monoxenous | TriTrypdb | TriTrypdb | N/A | 41.3 | 9489 |
| Endotrypanum monterogeii | Dixenous | TriTrypdb | TriTrypdb | N/A | 32.5 | 8285 |
| Herpetomonas muscarum | Monoxenous | NCBI | Orf/blastx REFSEQ | N/A | 30.8 | 10,297 |
| Leishmania amazonensis | Dixenous | Unicamp | Unicamp | PMID23857904 | 31.3 | 7316 |
| Leishmania arabica | Dixenous | TriTrypdb | TriTrypdb | N/A | 31.3 | 8646 |
| Leishmania aethiopica | Dixenous | TriTrypdb | TriTrypdb | N/A | 32.6 | 8722 |
| Leishmania enriettii | Dixenous | TriTrypdb | TriTrypdb | N/A | 30.8 | 8731 |
| Leishmania gerbilli | Dixenous | TriTrypdb | TriTrypdb | N/A | 31.4 | 8599 |
| Leishmania braziliensis | Dixenous | NCBI | NCBI | PMID26384787 | 35.2 | 8151 |
| Leishmania donovani | Dixenous | NCBI | NCBI | PMID22038251 | 32.4 | 7960 |
| Leishmania infantum | Dixenous | NCBI | NCBI | PMID29273719 | 32.4 | 8141 |
| Leishmania major | Dixenous | NCBI | NCBI | PMID16020728 | 32.3 | 8306 |
| Leishmania mexicana | Dixenous | NCBI | NCBI | PMID26452044 | 32.1 | 8137 |
| Leishmania panamensis | Dixenous | NCBI | NCBI | PMID25707621 | 31 | 7742 |
| Leishmania peruviana | Dixenous | NCBI | Orf/blastx REFSEQ | PMID26384787 | 33.4 | 7155 |
| Leptomonas pyrrhocoris | Monoxenous | NCBI | NCBI | PMID27021793 | 30.4 | 9284 |
| Leptomonas seymouri | Monoxenous | NCBI | NCBI | PMID26317207 | 27.1 | 8485 |
| Leishmania tarentolae | Dixenous | TriTrypdb | TriTrypdb | N/A | N/A | 8305 |
| Leishmania tropica | Dixenous | TriTrypdb | TriTrypdb | N/A | 32.3 | 8824 |
| Leishmania turanica | Dixenous | TriTrypdb | TriTrypdb | N/A | 32.2 | 8608 |
| Trypanosoma evansi | Monoxenous | TriTrypdb | TriTrypdb | N/A | N/A | 12,838 |
| Lotmaria passim | Monoxenous | NCBI | NCBI | PMID26146231 | 27.7 | 4850 |
| Perkinsela sp. | Obligate endosymbiont | NCBI | NCBI | PMID28916813 | 9.5 | 5192 |
| Phytomonas francai | Dixenous (plants) | NCBI | Orf/blastx REFSEQ | PMID28082482 | 17.7 | 6410 |
| Phytomonas sp. | Dixenous (plants) | NCBI | NCBI | PMID24516393 | 18 | 4905 |
| Phytomonas serpens | Dixenous (plants) | TriTrypdb | TriTrypdb | N/A | 25.7 | 7329 |
| Strigomonas galati | Endosymbiont-bearing monoxenous | NCBI | Orf/blastx REFSEQ | PMID24015778 | 27.2 | 6785 |
| Strigomonas culicis | Endosymbiont-bearing monoxenous | NCBI | Orf/blastx REFSEQ | PMID23560078 | 25.4 | 6778 |
| Strigomonas oncopelti | Endosymbiont-bearing monoxenous | NCBI | Orf/blastx REFSEQ | PMID24015778 | 25 | 9642 |
| Trypanosoma brucei | Dixenous | NCBI | NCBI | PMID16020726 | 26.5 | 8132 |
| Trypanosoma congolense | Dixenous | NCBI | NCBI | N/A | 39.2 | 19,062 |
| Trypanosoma cruzi | Dixenous | NCBI | NCBI | PMID24482508 | 30.4 | 7659 |
| Trypanosoma equiperdum | Dixenous | NCBI | NCBI | PMID28138343 | 26.2 | 10,001 |
| Trypanosoma grayi | Dixenous | NCBI | NCBI | PMID25977781 | 20.9 | 10,576 |
| Trypanosoma rangeli | Dixenous | NCBI | NCBI | PMID25233456 | 18.1 | 7331 |
| Trypanosoma theileri | Dixenous | TriTrypdb | TriTrypdb | N/A | 29.8 | 11,312 |
| Trypanosoma vivax | Dixenous | TriTrypdb | TriTrypdb | N/A | 24.7 | 11,362 |
| Paratrypanosoma | Monoxenous | NCBI | NCBI | PMID29078369 | 27.5 | 9606 |
1. Protein sequences were obtained from NCBI, TriTrypDB, or deduced from genome by obtaining open reading frames and adjusting starting Met by blastx to Protozoa-Refseq NCBI database; 2. After clusterization at 99% and removal of sequences smaller than 50 aa. N/A: not available.