Table 2.
Characteristics of genome-deduced proteomes (all* from VectorBase, www.vectorbase.org ) from hematophagous Diptera insects used in this work.
| Species | Order level | Family | Common name | Disease’s vector | Geneset version | Genome size (Mb) | Total number of sequences |
|---|---|---|---|---|---|---|---|
| Aedes aegypti | Nematocera, Culicomorpha | Culicidae | Yellow fever mosquito | Dengue, yellow fever, chikungunya and Zika (all viruses) | AaegL5.1 | 1278 | 16,355 |
| Aedes albopictus | Nematocera, Culicomorpha | Culicidae | Asian tiger mosquito | Dengue, La Crosse encephalitis and West Nile fever | AaloF1.2 | 1923 | 15,564 |
| Anopheles albimanus | Nematocera, Culicomorpha | Culicidae | American Malaria mosquito | Malaria (Plasmodium protozoan) | AalbS2.5 | 173 | 11,882 |
| Anopheles arabiensis | Nematocera, Culicomorpha | Culicidae | African Malaria mosquito | Malaria (Plasmodium protozoan) | AaraD1.8 | 247 | 13,221 |
| Anopheles atroparvus | Nematocera, Culicomorpha | Culicidae | European Malaria mosquito | Malaria (Plasmodium protozoan) | AatrE2.1 | 225 | 13,717 |
| Anopheles christyi | Nematocera, Culicomorpha | Culicidae | Mosquito | None; comparator species for A. gambiae complex | AchrA1.6 | 173 | 10,696 |
| Anopheles coluzzii | Nematocera, Culicomorpha | Culicidae | African Malaria mosquito | Malaria (Plasmodium protozoan) | AcolM1.6 | 225 | 14,502 |
| Anopheles culicifacies | Nematocera, Culicomorpha | Culicidae | Asian Malaria mosquito | Malaria (Plasmodium; Apicomplexa protozoan) | AculA1.5 | 203 | 14,138 |
| Anopheles darlingi | Nematocera, Culicomorpha | Culicidae | American Malaria mosquito | Malaria (Plasmodium protozoan) | AdarC3.7 | 137 | 10,493 |
| Anopheles dirus | Nematocera, Culicomorpha | Culicidae | Asian Malaria mosquito | Malaria (Plasmodium protozoan) | AdirW1.7 | 216 | 12,711 |
| Anopheles epiroticus | Nematocera, Culicomorpha | Culicidae | Asian Malaria mosquito | Malaria (Plasmodium protozoan) | AepiE1.6 | 223 | 11,854 |
| Anopheles farauti | Nematocera, Culicomorpha | Culicidae | Asian/Oceania Malaria mosquito | Malaria (Plasmodium protozoan) | AfarF2.4 | 172 | 12,967 |
| Anopheles funestus | Nematocera, Culicomorpha | Culicidae | African Malaria mosquito | Malaria (Plasmodium protozoan) | AfunF1.8 | 225 | 13,163 |
| Anopheles gambiae | Nematocera, Culicomorpha | Culicidae | African Malaria mosquito | Malaria (Plasmodium protozoan) | AgamP4.9 | 251 | 13,474 |
| Anopheles maculatus | Nematocera, Culicomorpha | Culicidae | Asian Malaria mosquito | Malaria (Plasmodium protozoan) | AmacM1.5 | 302 | 14,828 |
| Anopheles melas | Nematocera, Culicomorpha | Culicidae | African Malaria mosquito | Malaria (Plasmodium protozoan) | AmelC2.5 | 224 | 14,738 |
| Anopheles merus | Nematocera, Culicomorpha | Culicidae | African Malaria mosquito | Malaria (Plasmodium protozoan) | AmerM2.7 | 288 | 13,264 |
| Anopheles minimus | Nematocera, Culicomorpha | Culicidae | Asian Malaria mosquito | Malaria (Plasmodium protozoan) | AminM1.7 | 202 | 12,455 |
| Anopheles quadriannulatus | Nematocera, Culicomorpha | Culicidae | African Malaria mosquito | Malaria (Plasmodium protozoan) | AquaS1.9 | 283 | 13,168 |
| Anopheles sinensis | Nematocera, Culicomorpha | Culicidae | Asian Malaria mosquito | Malaria (Plasmodium protozoan) | AsinC2.2 | 298 | 19,247 |
| Anopheles stephensi | Nematocera, Culicomorpha | Culicidae | Asian Malaria mosquito | Malaria (Plasmodium protozoan) | AsteI2.3 | 223 | 11,699 |
| Culex quinquefasciatus | Nematocera, Culicomorpha | Culicidae | Southern house mosquito | lymphatic filariasis (worm), West Nile fever and St. Louis encephalitis (viruses) | CpipJ2.4 | 579 | 18,364 |
| Drosophila melanogaster1 | Brachycera, Muscomorpha | Drosophilidae | Fruit fly | None; comparator species for dipterans | – | 138 | 17,261 |
| Glossina austeni | Brachycera, Muscomorpha | Glossinidae | Tsetse fly | Animal African Trypanosomiasis (Trypanosoma protozoan) | GausT1.6 | 370 | 19,732 |
| Glossina brevipalpis | Brachycera, Muscomorpha | Glossinidae | Tsetse fly | Animal African Trypanosomiasis (Trypanosoma protozoan) | GbreI1.6 | 315 | 14,650 |
| Glossina fuscipes | Brachycera, Muscomorpha | Glossinidae | Tsetse fly | Human African Trypanosomiasis (Trypanosoma protozoan) | GfusI1.6 | 375 | 20,141 |
| Glossina morsitans | Brachycera, Muscomorpha | Glossinidae | Tsetse fly | Human and Animal African Trypanosomiasis (Trypanosoma protozoan) | GmorY1.9 | 355 | 12,507 |
| Glossina pallidipes | Brachycera, Muscomorpha | Glossinidae | Tsetse fly | Human African Trypanosomiasis (Trypanosoma protozoan) | GpalI1.6 | 357 | 19,308 |
| Lutzomyia longipalpis | Nematocera, Psychodomorpha | Psychodidae | Sand fly | American Visceral Leishmaniasis (Leishmania protozoan) | LlonJ1.4 | 154 | 10,284 |
| Musca domestica | Brachycera, Muscomorpha | Muscidae | House fly | None; comparator species for Glossina | MdomA1.3 | 636 | 15,116 |
| Phlebotomus papatasi | Nematocera, Psychodomorpha | Psychodidae | Sand fly | Old World cutaneous Leishmaniasis (Leishmania protozoan) | PpapI1.4 | 364 | 11,152 |
*Except for Drosophila; 1. Obtained from NCBI.