Table 2.

The GO function enrichment analysis of E2Fs and neighbor genes in PAAD (Metascape).

GO	Category	Description	Count	%	Log10(P)	Log10(q)
GO:0044843	GO Biological Processes	cell cycle G1/S phase transition	33	60	−48.77	−44.42
GO:0000307	GO Cellular Components	cyclin-dependent protein kinase holoenzyme complex	14	25.45	−27.08	−24.07
GO:0000083	GO Biological Processes	regulation of transcription involved in G1/S transition of mitotic cell cycle	11	20	−22.01	−19.28
GO:0008134	GO Molecular Functions	transcription factor binding	23	41.82	−21.19	−18.5
GO:0070317	GO Biological Processes	negative regulation of G0 to G1 transition	11	20	−20.06	−17.42
GO:0006260	GO Biological Processes	DNA replication	13	23.64	−13.39	−10.89
GO:0000785	GO Cellular Components	chromatin	16	29.09	−13.08	−10.58
GO:0034644	GO Biological Processes	cellular response to UV	9	16.36	−12.62	−10.13
GO:0016570	GO Biological Processes	histone modification	14	25.45	−11.88	−9.42
GO:0003712	GO Molecular Functions	transcription coregulator activity	15	27.27	−11.87	−9.41
GO:0033613	GO Molecular Functions	activating transcription factor binding	8	14.55	−10.75	−8.34
GO:0044839	GO Biological Processes	cell cycle G2/M phase transition	11	20	−10.74	−8.34
GO:0097472	GO Molecular Functions	cyclin-dependent protein kinase activity	6	10.91	−10.22	−7.84
GO:0008285	GO Biological Processes	negative regulation of cell proliferation	14	25.45	−8.95	−6.61
GO:1990841	GO Molecular Functions	promoter-specific chromatin binding	6	10.91	−8.92	−6.59
GO:0051052	GO Biological Processes	regulation of DNA metabolic process	11	20	−8.52	−6.21
GO:0007569	GO Biological Processes	cell aging	7	12.73	−8.08	−5.83
GO:0097124	GO Cellular Components	cyclin A2-CDK2 complex	3	5.45	−7.95	−5.71
GO:0071930	GO Biological Processes	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	3	5.45	−7.95	−5.71
GO:0090399	GO Biological Processes	replicative senescence	4	7.27	−7.77	−5.54