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. 2021 Feb 2;11:591337. doi: 10.3389/fphar.2020.591337

FIGURE 1.

FIGURE 1

A schematic diagram of network pharmacology approach for the identification of core targets, major hubs, PPI network, biological processes, and key pathways of vitamin C acting on CVD. All known targets of vitamin C and CVD were predicted using online databases. Then the targets of vitamin C with therapeutic potential for CVD were identified. After the construction of a PPI network and the identification of the hub targets of vitamin C acting on CVD, GO BP, and KEGG pathway enrichment analyses were performed. Finally, a network of vitamin C-CVD -GO-KEGG was generated.