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. 2021 Feb 2;11:602952. doi: 10.3389/fphar.2020.602952

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Copyright © 2021 Kumar, Belhaj, DiPette and Potts.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alginate-α-CGRP microcapsules delivery in two-day post-TAC mice improves cardiac functions. (A) Representative echocardiograms showing short axis B- and M-mode 2D echocardiography performed after 28 days of delivery of alginate-α-CGRP microcapsules in sham and TAC mice. Percentage fractional shortening (FS) and ejection fraction (EF) was calculated at various time points and plotted (B,C). *p < 0.05, TAC vs sham at the same time point; #p < 0.05, TAC-alginate-α-CGRP vs sham at the same time point; $p < 0.05, TAC vs TAC-alginate-α-CGRP at the same time point. @p < 0.05, TAC day 7 vs TAC day-2; and &p < 0.05, TAC-alginate-α-CGRP on day 7 vs TAC-alginate-α-CGRP on day-2.