Skip to main content
. 2021 Feb 15;11:3001. doi: 10.1038/s41598-020-79275-1

Table 2.

Comparison of 18 cat’s claw extracts from different manufacturer’s for reduction of Aβ 1–42 fibril and/or tau tangles.

Cat’s claw extract/product name/Company Major ingredients % reduction of A13 1–42
Fibrils (1:0.1 wt/wt)
% reduction of Tau
Tangles (1:1 wt/wt)
PTI-00703 cat’s claw (Cognitive Clarity Inc.) Cat’s claw (Uncaria tomentosa); 25 kg bags 51.2 90.1
GRUPO CENTROFLORA (Centroflora Group) Cat’s claw (Uncaria tomentosa) bark 39.3 86.6
GoNutra (GoNutra) Cat’s claw (Uncaria tomentosa) bark; bark powder in 1 lb bags 34.4 61.2
NOW (Now Foods) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 27.7 80.4
STARWEST BOTANICALS (Starwest Botanicals Inc.) Cat’s claw (Uncaria tomentosa) bark; bark powder in 1 25.6 64.9
SWANSON (Swanson Health Products) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 25.1 45.2
Peruvian Naturals (Peruvian Naturals) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 23.4 25.1
SOLARAY (Solaray) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 23.3 62.0

Best Naturals

(Best Naturals)

Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 21.5 48.7
PROGRESSIVE LABORATORIES (Progressive Laboratories) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 19.9 33.5
RAINTREE FORMULAS (Raintree Formulas) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 17.2 51.9

Herbal Plus

(General Nutrition Corp.)

Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 16.1 45.1
Remedy’s Nutrition (Remedy’s Nutrition) Cat’s claw (Uncaria tomentosa) bark 1000 mg capsules 15.9 60.2

Nature’s Way

(Nature’s Way Products Inc)

Cat’s claw (Uncaria tomentosa) bark; 335 mg capsules 15.4 64.2
NATURE’S HERBS (Nature’s Herbs) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 13.5 64.6
Pure Mountain BOTANICALS (Pure Mountain Botanicals) Cat’s claw (Uncaria tomentosa) bark; 500 mg capsules 12.2 51.0
PHARMLINE (Pharmline Inc.) Cat’s claw (Uncaria tomentosa) bark 500 mg capsules 9.5 60.3
elp essential (Essential Products) Cat’s claw (Uncaria tomentosa) bark; 700 mg capsules 8.0 20.2

Major ingredient details are also compared for each product.