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High expression of IgSF11 transcripts correlated to an immunosuppressive microenvironment of glioma patients. (A) CD4 and CD8 gene expression were elevated in high IgSF11 expression. (B) Anti-tumoral genes (IFNγ, Granzyme B, IL-2) exhibited no significant difference in high versus low IgSF11 expression profile. (C) TGFβ showed strong expression levels in glioma patients with high IgSF11 expression.
