Fig. 7.

ha-MSC loaded POx2-75 hydrogels reduced interstitial collagen deposition and infarct size and increased wall thickness in MI rat models. A. Picrosirius Red Staining showed collagen deposition in infarct, border and remote areas of infarcted hearts. Scale bar 200 μm. B. Quantification of collagen deposition. MI group (N = 3), MI + Gel group (N = 4) and MI + Gel + Cell group (N = 4). C and D. Quantification of infarct size and wall thickness. MI group (N = 3), MI + Gel group (N = 4) and MI + Gel + Cell group (N = 4). *p < 0.05; ****p < 0.0001. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)