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. 2021 Feb 11;14:647–657. doi: 10.2147/DMSO.S287582

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© 2021 Lu et al.

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SMS blocks NOX activation in STZ-induced DM rats. (A and B) Real-time quantitative polymerase chain reaction and quantitative analysis of NOX2 and NOX4 mRNA levels in heart tissues. (C–F) Representative Western blot and quantitative analyses of NOX2 and NOX4 protein levels in heart tissues. β-actin was used as the internal control. Results are presented as means ± standard deviations. **p < 0.01 vs the NC group; ^#p < 0.05 vs the DM group, and ^##p < 0.01 vs the DM group (n = 6 rats per group).