Table 3.
The Half-Maximal Inhibitory Concentration (IC50) Values of the MTT Assay Induced by THP Loaded PLGA Nanoparticles (200 nm & 400 nm) and Photo-Cytotoxicity Induced by the mTHPC Loaded Liposomes, Free mTHPC (Dissolved in DMSO) as Well as the LCNPs in SK-OV-3 Cells. The IC50 Values Were Calculated by Non-Linear Curve Fitting from the Graphs and Tabulated for the Respective Radiation Doses (Fluences)
| Formulations | Light Dose [mJ·cm−2] | IC50 [µM] |
|---|---|---|
| THP (DMSO) | – | 6.75 |
| THP NP 200 nm | – | 14.40 |
| THP NP 400 nm | – | 27.51 |
| mTHPC (DMSO) | 50 | 1.96 |
| 350 | 0.42 | |
| mTHPC-LP | 50 | 1.95 |
| 350 | 0.35 | |
| LCNP | 50 | 0.41 |
| 350 | 0.19 |