Table 3.
The topological characteristics of the top 30 target genes with the highest degree in the 16 overlapping DEmiRNA-target gene network. Typically, this table would be displaying only the top 30 target genes with the highest degree; since 26 target genes were ranked with the degree of 6, a total of 39 target genes with a degree ≥ 6 were finally listed in this table.
| Name | Degree | Average shortest path length | Betweenness centrality | Closeness centrality | Topological coefficient |
|---|---|---|---|---|---|
| BTG2 | 8 | 2.431705 | 0.003363 | 0.411234 | 0.18598065 |
| CCND2 | 8 | 2.517604 | 0.003716 | 0.397203 | 0.16845654 |
| NUFIP2 | 8 | 2.449032 | 0.003768 | 0.408325 | 0.18394988 |
| THBS1 | 8 | 2.231521 | 0.005344 | 0.448125 | 0.17855649 |
| UBN2 | 8 | 2.587281 | 0.004042 | 0.386506 | 0.17526212 |
| GIGYF1 | 8 | 2.589493 | 0.003609 | 0.386176 | 0.17635862 |
| CCND1 | 7 | 2.485899 | 0.002815 | 0.402269 | 0.19450361 |
| IGF1R | 7 | 2.426175 | 0.003724 | 0.412171 | 0.19710456 |
| IREB2 | 7 | 2.631152 | 0.00312 | 0.380062 | 0.20047142 |
| REL | 7 | 2.838341 | 0.002574 | 0.352318 | 0.19393939 |
| TNRC6A | 7 | 2.514286 | 0.002822 | 0.397727 | 0.20702541 |
| UHMK1 | 7 | 2.499171 | 0.002866 | 0.400133 | 0.20764488 |
| MDM2 | 7 | 2.519816 | 0.003737 | 0.396854 | 0.19915693 |
| ADAM10 | 6 | 2.52682 | 0.001899 | 0.395754 | 0.24168969 |
| CDKN1A | 6 | 2.667281 | 0.001979 | 0.374914 | 0.2337037 |
| EIF4G2 | 6 | 2.655853 | 0.001796 | 0.376527 | 0.23616084 |
| ELK4 | 6 | 2.542304 | 0.001911 | 0.393344 | 0.24100872 |
| ETNK1 | 6 | 2.726636 | 0.001859 | 0.366752 | 0.23112339 |
| HNRNPU | 6 | 2.652903 | 0.001945 | 0.376946 | 0.23472566 |
| HNRNPUL1 | 6 | 2.610876 | 0.001817 | 0.383013 | 0.23927525 |
| LRRC58 | 6 | 2.652903 | 0.001945 | 0.376946 | 0.23472566 |
| MAP1B | 6 | 2.741382 | 0.001822 | 0.364779 | 0.21069923 |
| NACC1 | 6 | 2.780092 | 0.002673 | 0.3597 | 0.22723133 |
| PANK3 | 6 | 2.901382 | 0.002215 | 0.344663 | 0.20067454 |
| PRDM2 | 6 | 2.437235 | 0.002245 | 0.410301 | 0.22983744 |
| PURB | 6 | 2.785622 | 0.002027 | 0.358986 | 0.2084477 |
| REV3L | 6 | 2.652166 | 0.001623 | 0.37705 | 0.23674815 |
| RREB1 | 6 | 2.823594 | 0.002115 | 0.354159 | 0.20654912 |
| SFT2D2 | 6 | 2.652166 | 0.001623 | 0.37705 | 0.23674815 |
| TET3 | 6 | 2.52682 | 0.001899 | 0.395754 | 0.24168969 |
| TMBIM6 | 6 | 2.52682 | 0.001899 | 0.395754 | 0.24168969 |
| TNPO1 | 6 | 2.567373 | 0.002674 | 0.389503 | 0.23314389 |
| ZNF264 | 6 | 2.627834 | 0.001775 | 0.380542 | 0.23815304 |
| ZNF678 | 6 | 2.57106 | 0.001949 | 0.388945 | 0.23931624 |
| ALDOA | 6 | 2.781198 | 0.002859 | 0.359557 | 0.21913299 |
| CCDC80 | 6 | 2.662488 | 0.00286 | 0.375588 | 0.20698404 |
| NF2 | 6 | 3.205161 | 0.002464 | 0.311997 | 0.2200685 |
| CBX6 | 6 | 2.693456 | 0.001811 | 0.37127 | 0.2316048 |
| DDX21 | 6 | 2.772719 | 0.001683 | 0.360657 | 0.22691611 |