Table 4.

DEmiRNA-transcription factor (TF) interaction network involved in DPSC and BMSC osteodifferentiation. The top 30 TFs with the highest degree of difference in the DEmiRNA-TF network of DPSCS and BMSCS osteodifferentiation were, respectively, ranked in the descending order of degree.

The top 30 TFs with the highest degree in DEmiRNAs-TF network of DPSC osteodifferentiation
Name	Degree	Average shortest path length	Betweenness centrality	Closeness centrality	Topological coefficient
FOXA1	30	1.954545	0.015768	0.511628	0.223996
BRD4	29	2.008021	0.009367	0.498003	0.244796
AR	29	2.029412	0.012695	0.492754	0.226894
MAX	29	1.997326	0.009458	0.500669	0.245836
EP300	28	1.981283	0.010644	0.504723	0.248155
ESR1	27	2.024064	0.01016	0.494055	0.226708
HIF1A	27	1.986631	0.01079	0.503365	0.245075
ERG	26	2.008021	0.008387	0.498003	0.265101
KDM5B	26	1.986631	0.008951	0.503365	0.259557
CTCF	25	2.034759	0.009876	0.491459	0.25205
MYC	25	2.013369	0.008083	0.49668	0.27092
RUNX1	24	2.034759	0.006933	0.491459	0.277477
SPI1	23	2.072193	0.00707	0.482581	0.250994
ZNF143	22	2.066845	0.00628	0.483829	0.255913
MAZ	22	2.050802	0.006421	0.487614	0.279362
ELF1	22	2.05615	0.005904	0.486346	0.298782
ARNTL	22	2.109626	0.005538	0.474018	0.27185
SP1	22	2.061497	0.007389	0.485084	0.278977
TCF3	21	2.088235	0.005238	0.478873	0.281495
PHF8	21	2.136364	0.004093	0.468085	0.295021
CEBPB	21	2.125668	0.006218	0.47044	0.272461
TCF12	21	2.114973	0.005147	0.472819	0.289542
TFAP2C	21	2.136364	0.006262	0.468085	0.266791
E2F1	20	2.040107	0.006168	0.49017	0.295552
TAF1	20	2.141711	0.004164	0.466916	0.29772
CTCFL	20	2.131016	0.004453	0.46926	0.301133
MED1	19	2.195187	0.003279	0.455542	0.301484
JUND	19	2.18984	0.005712	0.456654	0.264742
NOTCH1	19	2.088235	0.004576	0.478873	0.309831
KDM2B	19	2.147059	0.003495	0.465753	0.310989
LARP7	19	2.104278	0.004425	0.475222	0.316458
STAT1	19	2.125668	0.004486	0.47044	0.303774
E2F6	19	2.088235	0.00484	0.478873	0.274578
GATA3	19	2.163102	0.004673	0.462299	0.286357
TRIM28	19	2.147059	0.004839	0.465753	0.297788
The top 30 TFs with the highest degree in DEmiRNA-TF network of BMSC osteodifferentiation
Name	Degree	Average shortest path length	Betweenness centrality	Closeness centrality	Topological coefficient
MAX	20	2.021505	0.003652	0.494681	0.161047
AR	20	2.010753	0.010422	0.497326	0.149037
MYC	18	2.032258	0.002722	0.492063	0.175405
ESR1	18	2.02509	0.004109	0.493805	0.154739
MAZ	17	2.050179	0.003885	0.487762	0.163923
FOXA1	17	2.057348	0.004905	0.486063	0.139836
ERG	17	2.039427	0.002605	0.490334	0.182422
HIF1A	16	2.035842	0.00274	0.491197	0.186531
CREB1	16	2.046595	0.003777	0.488616	0.172636
EP300	15	2.050179	0.00182	0.487762	0.20078
CTCF	15	2.043011	0.002819	0.489474	0.177864
FLI1	14	2.057348	0.001999	0.486063	0.19308
BRD4	14	2.050179	0.001697	0.487762	0.205114
TP53	13	2.064516	0.002431	0.484375	0.200512
TFAP2C	13	2.071685	0.002276	0.482699	0.183618
TCF12	13	2.060932	0.001517	0.485217	0.214543
RUNX1	13	2.071685	0.001542	0.482699	0.210065
RAD21	13	2.0681	0.002309	0.483536	0.174057
KDM5B	13	2.057348	0.001707	0.486063	0.211276
CEBPB	13	2.071685	0.003446	0.482699	0.156718
TRIM28	12	2.0681	0.001403	0.483536	0.222766
TEAD4	12	2.064516	0.001834	0.484375	0.212077
STAT1	12	2.0681	0.001237	0.483536	0.229126
SPI1	12	2.075269	0.004133	0.481865	0.206451
PHF8	12	2.071685	0.001465	0.482699	0.222712
E2F1	12	2.0681	0.001526	0.483536	0.215917
TCF3	11	2.082437	0.001244	0.480207	0.225841
REST	11	2.057348	0.00601	0.486063	0.207061
NFE2	11	2.071685	0.00123	0.482699	0.231276
MYCN	11	2.071685	0.001787	0.482699	0.231098
LARP7	11	2.082437	0.001129	0.480207	0.235147
KDM2B	11	2.075269	0.00107	0.481865	0.23975
HEY1	11	2.078853	0.001289	0.481034	0.231113
ELF1	11	2.089606	0.001158	0.478559	0.227812
EBF1	11	2.075269	0.001284	0.481865	0.220856
ARNTL	11	2.082437	0.001177	0.480207	0.22781