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. 2021 Feb 2;96(5):e798–e808. doi: 10.1212/WNL.0000000000011231

Figure 2. Thigh Muscle Volume.

Figure 2

(A) Sample axial slice of the thigh including T1-weighted (top), short tau inversion recovery (STIR) (center), and volumetric thigh tissue composition (bottom) showing regions of unaffected muscle (red), STIR hyperintense muscle (yellow), and intramuscular fat (IMF) (purple). (B) Correlations between the volume of unaffected muscle (blue) and the combined volume of unaffected and STIR hyperintense muscle (red) in the thigh are shown. The correlation coefficients decrease when IMF volume is included (not shown): thigh strength (r = 0.38), lower extremity (LE) strength (r = 0.37), Inclusion Body Myositis Functional Rating Scale (IBMFRS) (r = 0.14), 6-minute walk test (6MWT) (r = 0.32), Adult Myopathy Assessment Tool (AMAT) total score (r = 0.28), and Activities-Specific Balance Confidence Scale (ABC) score (r = 0.30).