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. 2021 Feb 15;4(2):e2037356. doi: 10.1001/jamanetworkopen.2020.37356

Table 2. Usage Trends in Guideline Nonrecommended Tests and Treatments.

Service Guideline period 1 (2006-2014) Guideline period 2 (2014-2019) Change between guideline periods
Adjusted use, % (95% CI) Monthly slope (95% CI) Adjusted use, % (95% CI) Monthly slope (95% CI) Change in slope (95% CI)a Level change (95% CI)b
Start End Start End
Testing
ED group
Complete blood count 6.4 (5.1-7.7) 3.7 (2.4-5.0) −0.03 (−0.04 to −0.02) 4.0 (2.7-5.3) 2.3 (1.0-3.6) −0.02 (−0.03 to −0.003) 0.01 (−0.01 to 0.027) 0.3 (−0.3 to 1.0)
Chest radiograph 48.4 (44.0-52.9) 30.2 (25.9-34.5) −0.19 (−0.21 to −0.18) 25.9 (21.5-30.2) 14.2 (9.8-18.7) −0.13 (−0.17 to −0.09) 0.06 (0.02 to 0.10) −4.1 (−5.9 to −2.4)
Viral testing 23.5 (16.2-30.8) 22.6 (15.3-29.8) −0.01 (−0.04 to 0.01) 18.9 (11.6-26.1) 18.3 (11.0-25.6) −0.04 (−0.09 to −0.01) −0.03 (−0.08 to 0.03) −3.7 (−5.9 to −1.5)
Inpatient group
Complete blood count 44.6 (39.8-49.3) 32.2 (27.6-36.8) −0.13 (−0.16 to −0.11) 31.5 (26.8-36.1) 23.6 (18.8-28.3) −0.07 (−0.12 to −0.03) 0.07 (0.02 to 0.11) −0.8 (−2.7 to 1.1)
Chest radiograph 78.8 (75.6-82.1) 57.3 (54.2-60.4) −0.23 (−0.26 to −0.21) 51.1 (47.9-54.2) 37.3 (34.0-40.6) −0.23 (−0.27 to −0.19) 0.01 (−0.04 to 0.06) −6.3 (−8.1 to −4.4)
Viral testing 60.9 (55.3-66.6) 48.7 (43.1-54.2) −0.13 (−0.16 to −0.11) 41.4 (35.8-46.9) 33.5 (27.8-39.2) −0.11 (−0.16 to −0.05) 0.03 (−0.03 to 0.09) −7.3 (−9.6 to −5.0)
Treatment
ED group
Bronchodilators 56.3 (51.1-61.5) 46.1 (41.0-51.2) −0.11 (−0.13 to −0.09) 32.5 (27.3-37.7) 26.0 (20.8-31.2) −0.26 (−0.30 to −0.23) −0.15 (−0.20 to −0.11) −13.5 (−15.2 to −11.8)
Steroids 15.7 (13.0-18.3) 11.1 (8.5-13.7) −0.05 (−0.06 to −0.04) 9.0 (6.4-11.6) 6.1 (3.4-8.7) −0.04 (−0.06 to −0.01) 0.01 (−0.02 to 0.04) −2.0 (−3.1 to −0.9)
Antibiotics 4.2 (3.3-5.0) 3.6 (2.7-4.4) −0.01 (−0.01 to −0.001) 3.1 (2.2-3.9) 2.7 (1.8-3.6) 0.01 (−0.004 to 0.02) 0.01 (0.001 to 0.03) −0.5 (−1.0 to −0.01)
Inpatient group
Bronchodilators 73.0 (68.0-78.0) 65.8 (60.9-70.7) −0.08 (−0.10 to −0.05) 54.7 (49.8-59.6) 50.1 (45.1-55.1) −0.26 (−0.30 to −0.22) −0.18 (−0.23 to −0.13) −11.3 (−13.1 to −9.4)
Steroids 38.6 (35.3-42.0) 29.8 (26.7-32.9) −0.09 (−0.12 to −0.07) 23.6 (20.5-26.7) 17.9 (14.6-21.2) −0.08 (−0.13 to −0.03) 0.01 (−0.04 to 0.07) −6.2 (−8.5 to −3.9)
Antibiotics 49.1 (46.9-51.2) 34.0 (32.2-35.9) −0.16 (−0.19 to −0.14) 33.4 (31.5-35.2) 23.8 (21.6-25.9) −0.11 (−0.15 to −0.07) 0.06 (0.01 to 0.11) −0.7 (−2.7 to 1.3)
Balancing
Hospital admission rate 18.0 (13.8-22.2) 18.0 (13.8-22.2) 0.00 (−0.004 to 0.004) 17.9 (13.6-22.1) 17.8 (13.6-22.1) 0.02 (0.01 to 0.03) 0.02 (0.01 to 0.03) −0.02 (−0.01 to 0.03)
Length of stay, d 2.0 (1.9-2.1) 1.8 (1.7-1.9) −0.002 (−0.003 to −0.001) 1.9 (1.8-1.9) 1.7 (1.7-1.8) −0.002 (−0.003 to 0.000) 0.001 (0 to 0.002) 0.03 (0.02 to 0.08)

Abbreviation: ED, emergency department.

a

Change in slope is defined as the difference in slope between guideline period 1 and guideline period 2.

b

Level change is defined as the change in usage rate between the 2 time periods (ie, start of guideline period 2 vs end of guideline period 1) using 2014 guideline publication as the event point.