Table 2.
Parasitological parameters, lung pathology and preventive drug efficacy against larvae excretion and (pre-)adult of Aelurostrongylus abstrusus
| Group | Animal ID | First day of L1 excretion (dpi) | Max. L1 count/day in 5 g faeces | GM of max. L1 count/day | Efficacy (%) | Lung pathology score | (Pre-)adult worm count | GM of adult worms | Preventive efficacy (%) |
|---|---|---|---|---|---|---|---|---|---|
| 1 (treated 12 weeks prior to infection) | 0801 | n.a. | 0 | 1.10 | 99.99 | 1 | 0 | 0.09 | 99.66 |
| 1054 | 39 | 5 | 0 | 0 | |||||
| 2936 | n.a. | 0 | 1 | 0 | |||||
| 3881 | 37 | 1 | 0 | 0 | |||||
| 5300 | n.a. | 0 | 1 | 1 | |||||
| 6615 | n.a. | 0 | 0 | 0 | |||||
| 8860 | 39 | 31 | 1 | 0 | |||||
| 9657 | n.a. | 0 | 0 | 0 | |||||
|
2 (treated 8 weeks prior to infection) |
0370 | n.a. | 0 | 1.19 | 99.99 | 0 | 0 | 0.00 | 100 |
| 3599 | 36 | 1 | 0 | 0 | |||||
| 5820 | n.a. | 0 | 2 | 0 | |||||
| 6242 | 37 | 25 | 1 | 0 | |||||
| 6554 | n.a. | 0 | 0 | 0 | |||||
| 7273 | 42 | 9 | 0 | 0 | |||||
| 7707 | n.a. | 0 | 1 | 0 | |||||
| 8219 | n.a. | 0 | 0 | 0 | |||||
|
3 (treated 4 weeks prior to infection) |
0862 | n.a. | 0 | 0.53 | 99.98 | 0 | 0 | 0.00 | 100 |
| 1160 | n.a. | 0 | 0 | 0 | |||||
| 1291 | n.a. | 0 | 0 | 0 | |||||
| 3550 | 41 | 1 | 1 | 0 | |||||
| 6179 | 44 | 9 | 0 | 0 | |||||
| 6676 | n.a. | 0 | 0 | 0 | |||||
| 9914 | n.a. | 0 | 1 | 0 | |||||
|
4 (untreated control) |
1151 | 33 | 45,900 | 7574.29 | 99.99 | 3 | 23 | 26.57 | n.a. |
| 1465 | 36 | 7400 | 3 | 36 | |||||
| 1509 | 40 | 54 | 4 | 10 | |||||
| 1588 | 38 | 1200 | 3 | 15 | |||||
| 6407 | 33 | 43,100 | 4 | 64 | |||||
| 6646 | 33 | 45,300 | 3 | 56 | |||||
| 9013 | 36 | 11,300 | 3 | 23 | |||||
| 9335 | 32 | 21,900 | 3 | 23 |
dpi = day post infection, max. = maximum, GM = geometric mean, n.a. = not applicable