Table 1.
Baseline patient and lesion characteristics
| Variables | Vildagliptin group (n = 10) | Control group (n = 10) | p Value |
|---|---|---|---|
| Men, % | 100 | 80 | 0.474 |
| Age, years | 65.9 ± 10.6 | 68.3 ± 8.1 | 0.820 |
| BMI, kg/m2 | 24.0 ± 4.0 | 24.0 ± 4.5 | 0.909 |
| Smoker, % | 70 | 40 | 0.133 |
| Familial history, % | 10 | 10 | 1.000 |
| Stable angina, % | 100.0 | 100.0 | |
| Revascularization vessel, % | 0.409 | ||
| Right coronary artery, % | 31.8 | 34.6 | |
| Left main coronary trunk, % | 18.2 | 7.7 | |
| Left anterior descending coronary artery, % | 31.8 | 34.6 | |
| Left circumflex coronary artery, % | 18.2 | 23.1 | |
| Medication, % | |||
| Beta blocker, % | 70.0 | 50.0 | 0.649 |
| ACE-I/ARB, % | 50.0 | 50.0 | 1.000 |
| Statin, % | 90.0 | 100.0 | 1.000 |
| Other oral DM drugs, % (except DPP-4 inhibitors) | 0.0 | 0.0 | |
| Insulin, % | 0.0 | 0.0 | |
| Prasugrel, % | 40.0 | 60.0 | 0.656 |
| Clopidogrel, % | 60.0 | 40.0 | 0.656 |
| Aspirin, % | 100.0 | 100.0 | 0 |
| Laboratory data | |||
| LDL cholesterol, mg/dl | 84.0 ± 14.3 | 82.9 ± 27 | 0.791 |
| HDL cholesterol, mg/dl | 47.4 ± 14.8 | 41.5 ± 9.8 | 0.289 |
| Triglyceride, mg/dl | 118.4 ± 52.1 | 131.6 ± 77.9 | 0.939 |
| Creatinine, mg/dl | 0.8 ± 0.1 | 0.9 ± 0.3 | 1.000 |
| 1,5 AG, μg/ml | 19.9 ± 4.1 | 22.0 ± 4.1 | 0.377 |
| HbA1c (NGSP), % | 5.9 ± 0.3 | 5.9 ± 0.4 | 0.845 |
| HOMA R | 1.5 ± 5.7 | 1.5 ± 0.6 | 0.909 |
| CRP, mg/dl | 0.2 ± 0.4 | 0.2 ± 0.2 | 0.879 |
| 75 g OGTT | |||
| Fast glucose, mg/dl | 97.2 ± 9.0 | 94.2 ± 11.9 | 0.471 |
| 2-h glucose, mg/dl | 185.7 ± 36.6 | 169.5 ± 20.5 | 0.405 |
| Fast IRI, μU/ml | 6.6 ± 3.5 | 6.3 ± 2.7 | 1.000 |
| 2-h IRI, μU/ml | 114.1 ± 80.3 | 101.3 ± 75.6 | 0.791 |
Mean ± standard deviation (n) for continuous variables; frequency count (%) for categorical variables 1,5 AG = 1,5 anhydroglucitol; 75 g OGTT = 75 g oral glucose tolerance test; ACE-I = angiotensin converting enzyme-inhibitor; ARB = angiotensin II receptor blocker; BMI = body mass index; CRP = C-reactive protein; DM = diabetes mellitus; DPP-4 = dipeptidyl peptidase-4; HbA1c = glycated hemoglobin; HDL = high-density lipoprotein; HOMA R = homeostasis model assessment ratio; IRI = immunoreactive insulin; LDL = low-density lipoprotein; NGSP = national glycohemoglobin standardization program