Table 1.
Association of thyroid antibodies with baseline characters in hypothyroid pregnancies
| Anti-TPO | P value | Anti-TG | P value | |||
|---|---|---|---|---|---|---|
| Positive N (%) N = 97 |
Negative N (%) N = 49 |
Positive N (%) N = 76 |
Negative N (%) N = 70 |
|||
| Age Groups | ||||||
| Age 20–25 | 8 (8.2) | 8 (16.3) | 8 (10.5) | 8 (11.4) | ||
| Age 26–30 | 41 (42.3) | 20 (40.8) | 0.243 | 27 (35.5) | 34 (48.6) | 0.363 |
| Age 31–35 | 28 (28.9) | 16 (32.7) | 27 (35.5) | 17 (24.3) | ||
| Age 36 and above | 20 (20.6) | 5 (10.2) | 14 (18.4) | 11 (15.7) | ||
| Paritya | ||||||
| Nulliparous | 30 (31.9) | 20 (42.6) | 0.213 | 22 (29.7) | 28 (41.8) | 0.135 |
| Multiparous | 64 (68.1) | 27 (57.4) | 52 (70.3) | 39 (58.2) | ||
| BMI | ||||||
| Underweight (< 18.5) | 4 (4.7) | 2 (4.7) | 3 (4.6) | 3 (4.7) | ||
| Normal (18.5–24.9) | 33 (38.4) | 13 (30.2) | 25 (38.5) | 21 (32.8) | ||
| Overweight (25–29.9) | 30 (34.9) | 15 (34.9) | 0.826b | 25 (38.5) | 20 (31.2) | 0.565b |
| Obesity class I (30–34.9) | 16 (18.6) | 11 (25.6) | 10 (15.4) | 17 (26.6) | ||
| Obesity class II and above (> = 35) | 3 (3.5) | 2 (4.7) | 2 (3.1) | 3 (4.7) | ||
| Pre-Gestational Diabetes | ||||||
| Yes | 2 (2.1) | 6 (12.2) | 0.018b | 2 (2.7) | 6 (8.6) | 0.155b |
| No | 94 (97.9) | 43 (87.8) | 73 (97.3) | 64 (91.4) | ||
| Gestational Diabetes | ||||||
| Yes | 21 (21.9) | 5 (10.2) | 0.083 | 12 (16.0) | 14 (20.0) | 0.530 |
| No | 75 (78.1) | 44 (89.8) | 63 (84.0) | 56 (80.0) | ||
| Hypertension | ||||||
| No | 84 (87.5) | 38 (77.6) | 65 (86..7) | 57 (81.4) | ||
| Gestational Hypertension/Pre-eclampsia | 6 (6.2) | 7 (14.3) | 0.248b | 4 (5.3) | 9 (12.9) | 0.250b |
| Chronic Hypertension | 6 (6.2) | 4 (8.2) | 6 (8.0) | 4 (5.7) | ||
Anti-TPO anti-thyroid peroxidase antibodies, Anti-TG anti-thyroglobulin antibodies, BMI Body mass index. P-values calculated by Chi-square test applied. aData of 5 cases are missing. bFischer exact test applied