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. 2021 Feb 15;21:136. doi: 10.1186/s12884-021-03594-y

Table 6.

Association of independent variables with premature birth adjusted for anti-thyroid peroxidase (Anti-TPO) and anti-thyroglobulin (Anti-TG) antibodies on multivariate logistic regression

Unadjusted OR (95% CI) P-value Adjusted OR (95% CI) P-value Unadjusted OR (95% CI) P-value Adjusted OR (95% CI) P-value
ANTI-THYROID PEROXIDASE ANTI-THYROGLOBULIN
Yes 1 0.328 1 0.58 1 0.32 1 0.46
No 1.51 (0.65–3.47) 1.39 (0.57–3.39) 1.56 (0.69–3.55) 1.44 (0.43–3.64)
AGE GROUPS
Age 20–25 1 1
Age 26–30 3.124 (0.82–11.77) 0.19 3.124 (0.82–11.77) 0.19
Age 31–35 2.5 (0.87–2.43) 2.5 (0.87–2.43)
Age 36 and above 2.25 (0.67–7.53) 2.25 (0.67–7.53)
PARITY
Nulliparous 1 1
Primiparous 0.48(0.17–1.36) 0.30 0.48(0.17–1.36) 0.30
Biparous/mutiparous 0.54 (0.20–1.45) 0.54 (0.20–1.45)
BODY MASS INDEX
Underweight/Normal 1 0.529 1 0.529
Overweight/obese 1.31 (0.55–3.10) 1.31 (0.55–3.10)
PRE GESTATIONAL DIABETES
Yes 1.24 (0.22–6.74) 0.80 1.24 (0.22–6.74) 0.80
No 1 1
GESTATIONAL DIABETES
Yes 2.35 (0.93–5.92) 0.07 2.35 (0.93–5.92) 0.07
No 1 1
HYPERTENSION
No 1 1 1 1
Pre-eclampsia/ Gestational Hypertension 2. 65(1.81–8.63) 0.002 2.48 (0.72–8.53) 0.03* 2. 65(1.81–8.63) 0.002 2.46(0.83–8.77) 0.05*
Chronic Hypertension 12.74 (2.34–36.91) 12.71 (2.37–67.99) 12.74 (2.34–36.91) 11.34 (2.63–64.34)

*Fischer test applied. P-value significant at <=0.05