TABLE 2.

Fecal miRNAs and bacteria correlated with them in different gastrointestinal disorders.

Fecal miRNAs	Diseases	Up/down	Correlated microbiome taxa	References
miRNA-135b	CRC	Up	–	Wu et al., 2014
miR-21	CRC	Up	–	Link et al., 2010
miR-106a	CRC	Up	–	Link et al., 2010
miR-182	CRC	Up	Blautia	Yuan et al., 2018
miR-139	CRC	Down	Blautia	Yuan et al., 2018
miR-155	IBD	Up	–	Schönauen et al., 2018
miR-223	IBD	Up	–	Schönauen et al., 2018
miR-199a	IBD	Up	–	Ji et al., 2018
miR-223-3p	IBD	Up	–	Ji et al., 2018
miR-1226	IBD	Down	–	Ji et al., 2018
miR-515-5p	IBD	Down	–	Ji et al., 2018

Up and down indicate upregulated and downregulated fecal miRNA expression levels in diseased tissues compared with normal tissues, respectively. Correlated microbiome taxa, bacteria significantly correlated with fecal miRNAs; CRC, colorectal cancer; IBD, inflammatory bowel disease.