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. 2020 Dec 17;12(3):880–895. doi: 10.1039/d0sc03175e

Table 1. Stoichiometry (N) and dissociation constant (Kd) obtained by ITC for the binding of nTBP-CTPR2n proteins to hTNKS2 ARC4. For each protein, the values listed are from two independent experiments.

Protein Stoichiometry (N) K d (μM)
1TBP-CTPR2 1.01 ± 0.03 14.68 ± 0.99
0.90 ± 0.02 12.80 ± 1.10
2TBP-CTPR4 2.18 ± 0.02 11.89 ± 0.26
2.05 ± 0.01 18.59 ± 0.39
3TBP-CTPR6 2.72 ± 0.03 5.62 ± 0.21
2.77 ± 0.02 20.12 ± 0.39
4TBP-CTPR8 3.38 ± 0.01 13.61 ± 0.19
2.91 ± 0.03 15.48 ± 0.43