TABLE 3.

Comparison of clinical and molecular features between LUAD samples of TP53 c.1010G>A carriers and non-carriers.

Features	Carriers, N = 7	Non-carriers, N = 579
Median age at diagnosis, years (IR)*	60 (10)	67 (16)
Histological subtype, N (%)	4 (57.1)	68 (11.7)
Acinar	1 (14.3)	46 (7.9)
Lepidic	3 (42.8)	22 (3.8)
Patients with other somatic alterations, N (%)†	5 (71.4)	497 (85.8)
EGFR mutation	4 (57.1)	102 (17.6)
KRAS mutation	0	148 (25.6)
BRAF mutation	0	15 (2.6)
Median age at diagnosis restricted to EGFR-mutant subtype, years (IR)	61 (16)	67.5 (20)

*IR, interquartile range.

^†A total of 502/586 LUAD cases were tested for somatic EGFR, KRAS, BRAF, and NRAS mutations.