Table 5.
False discovery rates (FDR) of protein classes enriched with up- and down-regulated genes in the challenged-only group compared to the other groups.
| Challenged-only group compared to: | |||
|---|---|---|---|
| Negative control | Vaccinated-and-challenged | Vaccinated-only | |
| Up-regulated genes | |||
| Defence/immunity protein | 1.08E-07 | 1.41E-07 | 1.86E-07 |
| Cytokine | 3.26E-05 | 1.13E-03 | 3.70E-05 |
| Immunoglobulin receptor superfamily | 1.61E-03 | 7.31E-04 | 3.40E-03 |
| Signaling molecule | 3.22E-03 | 9.17E-03 | 2.52E-03 |
| Chemokine | 1.13E-03 | 2.88E-03 | |
| Major histocompatibility complex antigen | 3.63E-03 | 3.19E-03 | |
| Microtubule binding motor protein | 4.32E-03 | 4.89E-03 | |
| Replication origin binding protein | 8.09E-03 | ||
| Cytokine receptor | 7.25E-03 | ||
| Down-regulated genes | |||
| Nucleic acid binding | 5.21E-07 | 8.21E-09 | 7.46E-08 |
| Microtubule family cytoskeletal protein | 7.45E-07 | 3.07E-10 | 1.02E-10 |
| Cytoskeletal protein | 2.57E-06 | 4.53E-09 | 5.45E-08 |
| RNA binding protein | 1.19E-03 | 3.75E-04 | |
| DNA binding protein | 4.06E-03 | ||
A false discovery rate (FDR) of < 0.01 was considered significant.