Table 1.
score criteria for liver inflammation
| Numerical grade or stage | Score |
|---|---|
| Periportal or periseptal interface hepatitis (piecemeal necrosis) | |
| Absent | 0 |
| Mild (focal, few portal areas) | 1 |
| Mild/moderate (focal, most portal areas) | 2 |
| Moderate (continuous ~60% of tracts or septa) | 3 |
| Severe (continuous around >50% of tracts or septa) | 4 |
| Confluent necrosis | 0 |
| Absent | 0 |
| Focal confluent necrosis | 1 |
| Zone 3 necrosis in some areas | 2 |
| Zone 3 necrosis in most areas | 3 |
| Zone 3 necrosis+occasional portal-central (P-C) bridging | 4 |
| Zone 3 necrosis+multiple P-C bridging | 5 |
| Focal confluent necrosis | 6 |
| Focal (spotty) lytic necrosis, apoptosis and focal inflammation | |
| Absent | 0 |
| One focus or less per 10 × objective | 1 |
| Two to four foci per 10 × objective | 2 |
| Five to 10 foci per 10 × objective | 3 |
| More than 10 foci per 10 × objective | 4 |
| Portal inflammation | |
| None | 0 |
| Mild, some or all portal areas | 1 |
| Moderate, some or all portal areas | 2 |
| Moderate/marked, all portal areas | 3 |
| Marked, all portal areas | 4 |