FIG 2.
Comparative linear map of plasmids pAC1633-1 and pAC1530. Arrows indicate the extents and directions of genes and ORFs. The blaNDM-1 and blaOXA-58 genes are colored in gold, other antimicrobial resistance genes are in yellow. Putative transcriptional activators are in pink, including the genes encoding the two-component regulatory proteins adeR and adeS that control transcription of the adeABC efflux pump. Transposases encoded by full-copy IS elements are shown in dark blue, whereas transposases without their corresponding IS elements or transposons in full are depicted in light blue. Genes with homology to conjugative transfer or type IV secretion system genes are in dark green. GD578_19675 refers to the ORF in the conjugative region of pAC1530 that was the site of insertion for ISAba11 in pAC1633-1. Color codes for the other genes are as indicated. Tn125 that harbors the blaNDM-1 gene is labeled. The extent of regions with >99% nucleotide sequence identities are indicated in the gray-shaded area.