TABLE 4.

Results from PERMANOVA-based Omnibus test combining different distance metrics comparing the associations between the vaginal microbiota and clinical variables

Clinical variable	UniFrac	GUniFrac	WUniFrac	BC	Omnibus P valuea
Pregnancy outcome (term vs preterm delivery)	0.014	0.001	0.001	0.001	0.001
Progesterone level	0.426	0.162	0.171	0.001	0.001
Estradiol level	0.654	0.056	0.055	0.003	0.006
Pregnancy status (multigravid vs primigravid)	0.442	0.079	0.079	0.289	0.186
Age above 35 yr	0.137	0.332	0.319	0.914	0.302
Delivery mode (caesarian section vs vaginal delivery)	0.435	0.26	0.253	0.180	0.377

^aBoldface indicates significance.