TABLE 3.

Frequency of cointegrate formation between mixed pairs of IS

ISb	Target	Cointegration frequencya
		Range	Mean (SD)
IS26	R388::IS1006	2.1 × 10−7 to 1.7 × 10−6	8.1 × 10−7 (7.6 × 10−7)
IS26	R388::IS1008	4.6 × 10−7 to 6.9 × 10−7	6.6 × 10−7 (3.3 × 10−7)
IS26	R388:: IS1006/1008	6.6 × 10−7 to 8.9 × 10−7	7.6 × 10−7 (1.2 × 10−7)
IS1006	R388::IS26	6.9 × 10−7 to 1.3 × 10−6	9.9 × 10−7 (3.1 × 10−7)
IS1006	R388::IS1008	1.5 × 10−7 to 6.0 × 10−7	4.0 × 10−7 (2.3 × 10−7)
IS1006	R388:: IS1006/1008	5.9 × 10−7 to 8.4 × 10−7	6.9 × 10−7 (1.3 × 10−7)
IS1008	R388::IS26	2.2 × 10−7 to 1.7 × 10−6	3.7 × 10−7 (1.8 × 10−7)
IS1008	R388::IS1006	5.2 × 10−7 to 6.9 × 10−7	5.9 × 10−7 (9.1 × 10−8)
IS1008c	R388:: IS1006/1008	4.5 × 10−5 to 6.7 × 10−5	5.6 × 10−5 (1.1 × 10−5)
IS1006/1008	R388::IS26	5.7 × 10−7 to 1.4 × 10−6	9.0 × 10−7 (4.7 × 10−7)
IS1006/1008	R388::IS1006	1.4 × 10−7 to 8.2 × 10−7	5.6 × 10−7 (3.7 × 10−7)
IS1006/1008c	R388::IS1008	2.5 × 10−5 to 5.4 × 10−5	4.2 × 10−5 (1.5 × 10−5)
IS26::catA1c	R388::IS26	3.2 × 10−4 to 7.6 × 10−4	5.5 × 10−4 (2.2 × 10−4)

^aFrequency measured as cointegrates per transconjugant. Three independent determinations were made per experiment.

^bIS in the pUC19 backbone.

^cShading indicates frequencies that are consistent with the targeted conservative reaction.