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The explained variance in TG levels using a polygenic risk score in FHTG and CHTG
| Group | Explained variance (%) [IC 0.025–0.975] |
P |
|---|---|---|
| FHTG | 1.78 [0.45–4.47] | < 2.2 × 10−16 |
| CHTG | 6.73 [0.47–9.56] |
IC from bootstrapped R-squared of models performing linear regression of TG levels on polygenic scores. The polygenic risk score was computed using the complete set of 38 known TG associated variants. P value of the comparison between the variance explained in FHTG versus CHTG
