Table 1.

Clinical Case Laboratory Evaluation

Laboratory test	Result (reference range)
Serum midnight cortisol	17.3 mcg/dL (<1.8; >7.5 indicative of hypercortisolemia)
24-hour urine free cortisol	196 mcg/24h (3.5-45)
Suppression in 24-hour urine free cortisol on day-6 of the Liddle test compared to baseline urine free cortisol	17% (>90%)
ACTH	<5 pg/mL (5-46)
Plasma renin activity	1.06 ng/mL/h (mean 1.9)
Plasma aldosterone concentration	2 ng/dL (≤21)
24-hour urine metanephrines	101 mcg/24h (30-18 [normotensive]; <400 [hypertensive])
24-hour urine normetanephrine	380 mcg/24h (111-419 [normotensive]; <900 [hypertensive])
24-hour urine total metanephrine	481 mcg/24h (149-535 [normotensive]; <1300 [hypertensive])