Table 3.
Distribution of SNP rs1044250 genotypes and alleles in Mets and Mets components
| n | Genotypes | χ2 | p | Alleles | χ2 | p | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| CC | CT | TT | C | T | ||||||
| Mets | ||||||||||
| Control group | 1029 | 900 (87.5%) | 125 (12.1%) | 4 (0.4%) | 25.556 | < 0.001 | 1925 (93.5%) | 133 (6.5%) | 25.991 | < 0.001 |
| Mets group | 1018 | 811 (79.7%) | 191 (18.8%) | 16 (1.6%) | 1847 (90.7%) | 189 (9.3%) | ||||
| Component | ||||||||||
| Normal BP | 961 | 760 (86.9%) | 111 (12.7%) | 4 (0.5%) | 13.68 | 0.001 | 1631 (93.2%) | 119 (6.8%) | 13.834 | < 0.001 |
| Elevated BP | 1169 | 951 (81.1%) | 205 (17.5%) | 20 (1.0%) | 2107 (89.1%) | 237 (10.1%) | ||||
| Normal TG | 1347 | 1164 (85.0%) | 196 (14.3%) | 10 (0.7%) | 6.96 | 0.031 | 2524 (92.1%) | 216 (7.9%) | 6.888 | 0.009 |
| Increased TG | 688 | 547 (80.8%) | 120 (17.7%) | 10 (0.7%) | 1214 (89.7%) | 140 (10.3%) | ||||
| Normal WC | 1318 | 1009 (86.8%) | 149 (12.8%) | 4 (0.3%) | 26.308 | < 0.001 | 2441 (92.6%) | 195 (7.4%) | 9.741 | 0.002 |
| Increased WC | 717 | 702 (79.3%) | 167 (18.9%) | 16 (1.8%) | 1299 (90.6%) | 135 (9.4%) | ||||
| Normal FPG | 1721 | 1324 (84.8%) | 222 (14.2%) | 15 (1.0%) | 7.504 | 0.023 | 2870 (91.9%) | 252 (8.1%) | 6.447 | 0.011 |
| Increased FPG | 314 | 387 (79.6%) | 94 (19.3%) | 5 (1.0%) | 868 (89.3%) | 104 (10.7%) | ||||
| Normal HDL | 1811 | 1216 (83.5%) | 225 (15.5%) | 15 (1.0%) | 0.15 | 0.928 | 2657 (91.2%) | 255 (8.8%) | 0.048 | 0.827 |
| Decreased HDL | 224 | 495 (83.8%) | 91 (15.4%) | 5 (0.8.%) | 1081 (91.5%) | 101 (8.5%) | ||||
Mets, metabolic syndrome; BP, blood pressure; TG, triglyceride; HDL-c, high-density lipoprotein-cholesterol; WC, waist circumference; FPG, fasting plasma glucose