Table 1.
CYP2C8 genotype and allele frequencies in Zanzibar
| Relative and (absolute) CYP2C8 genotype frequencies | Relative and (absolute) CYP2C8 allele frequencies | ||
|---|---|---|---|
| 2C8*1/2C8*1 | 0.634 (392) | 2C8*1 | 0.798 (987) |
| 2C8*2/2C8*2 | 0.024 (15) | 2C8*2 | 0.175 (216) |
| 2C8*3/2C8*3 | 0.005 (3) | 2C8*3 | 0.027 (33) |
| 2C8*1/2C8*2 | 0.293 (181) | ||
| 2C8*1/2C8*3 | 0.036 (22) | ||
| 2C8*2/2C8*3 | 0.008 (5) | ||
Relative and absolute (n) frequencies among 618 children under 5 years old with uncomplicated falciparum malaria. The 2C8*2/2C8*3 genotype are individuals (n=5) that were heterozygous carriers for both CYP2C8*2 and CYP2C8*3. For these, 5 alleles were attributed each to the 2C8*2 and 2C8*3 allele frequencies