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. 2021 Feb 15;16:13. doi: 10.1186/s13027-021-00347-6

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Low NSD1, NSD2, or NSD3 expression is strongly associated with reduced survival in patients with HPV+ but not HPV- HNSCC. Overall survival of patients grouped by high, mid, or low expression of NSD1, NSD2, or NSD3 in the HPV+ (a) and HPV- (b) HNSCC cohorts. Comparison between groups were calculated with the 2-sided log-rank test (p value) and multiple comparisons corrected with the Benjamini–Hochberg method utilizing an FDR threshold of 10% (q value). Numbers in brackets indicate the number of samples included in each expression group