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. 2021 Feb 16;94:107479. doi: 10.1016/j.intimp.2021.107479

Table 2.

Comparison of immune factors in controls and stress group.

Variable Controls (n = 152) Pre-stress (n = 76) Post-stress (n = 76) P
WBC (109/L) 5.47 ± 1.24 5.39 ± 1.17 5.59 ± 1.27 0.594
M 5.95 ± 1.17 5.74 ± 1.46 6.19 ± 1.27 0.621
F 5.37 ± 1.23 5.30 ± 1.08 5.44 ± 1.23 0.812
Doctor 5.66 ± 1.25 5.48 ± 1.28 6.26 ± 1.33 0.165
Nurse 5.42 ± 1.23 5.37 ± 1.15 5.40 ± 1.19 0.962
NEUT (109/L) 3.10 ± 0.92 3.18 ± 0.89 3.00 ± 0.92 0.506
M 3.17 ± 0.77 3.18 ± 1.02 3.11 ± 0.89 0.965
F 3.08 ± 0.96 3.18 ± 0.86 2.98 ± 0.93 0.503
Doctor 3.11 ± 1.00 3.04 ± 0.70 3.24 ± 0.74 0.793
Nurse 3.09 ± 0.91 3.22 ± 0.94 2.94 ± 0.96 0.259
LYM (109/L) 1.89 ± 0.52 1.77 ± 0.50 2.18 ± 0.59**## <0.001
M 2.19 ± 0.55 2.05 ± 0.68 2.62 ± 0.63# 0.027
F 1.82 ± 0.49 1.70 ± 0.42 2.07 ± 0.53**## <0.001
Doctor 2.00 ± 0.50 1.96 ± 0.74 2.54 ± 0.72*# 0.009
Nurse 1.85 ± 0.52 1.71 ± 0.39 2.08 ± 0.51*## <0.001
MONO (109/L) 0.35 ± 0.09 0.34 ± 0.08 0.28 ± 0.07**## <0.001
M 0.40 ± 0.09 0.39 ± 0.12 0.32 ± 0.08*↓ 0.049
F 0.34 ± 0.09 0.33 ± 0.07 0.27 ± 0.07**## <0.001
Doctor 0.38 ± 0.09 0.36 ± 0.11 0.34 ± 0.08 0.290
Nurse 0.34 ± 0.09 0.34 ± 0.08 0.27 ± 0.07**## <0.001
EOS (109/L) 0.10 ± 0.09 0.09 ± 0.07 0.10 ± 0.07 0.265
M 0.15 ± 0.13 0.11 ± 0.08 0.11 ± 0.05 0.372
F 0.09 ± 0.07 0.08 ± 0.06 0.10 ± 0.08 0.340
Doctor 0.13 ± 0.12 0.10 ± 0.08 0.12 ± 0.05 0.611
Nurse 0.10 ± 0.07 0.08 ± 0.07 0.10 ± 0.08 0.399
BASO (109/L) 0.03 ± 0.02 0.02 ± 0.02 0.02 ± 0.01**↓ <0.001
M 0.04 ± 0.02 0.02 ± 0.02 0.03 ± 0.02 0.071
F 0.03 ± 0.01 0.02 ± 0.02 0.02 ± 0.01**↓ <0.001
Doctor 0.03 ± 0.02 0.02 ± 0.02 0.03 ± 0.02 0. 100
Nurse 0.03 ± 0.01 0.02 ± 0.02 0.02 ± 0.01**↓ <0.001
NLR 1.72 ± 0.58 1.90 ± 0.65 1.45 ± 0.56**## <0.001
M 1.51 ± 0.45 1.64 ± 0.58 1.22 ± 0.40 0.054
F 1.77 ± 0.60 1.96 ± 0.65 1.51 ± 0.58*## <0.001
Doctor 1.64 ± 0.64 1.71 ± 0.60 1.32 ± 0.32 0.098
Nurse 1.75 ± 0.57 1.95 ± 0.65 1.49 ± 0.61*## <0.001
MLR 0.19 ± 0.05 0.20 ± 0.06 0.13 ± 0.03**## <0.001
M 0.19 ± 0.05 0.20 ± 0.07 0.13 ± 0.04**## 0.001
F 0.20 ± 0.06 0.21 ± 0.06 0.13 ± 0.03**## <0.001
Doctor 0.20 ± 0.05 0.20 ± 0.07 0.14 ± 0.04**## 0.001
Nurse 0.19 ± 0.06 0.21 ± 0.06 0.13 ± 0.03**## <0.001
NEUT ratio (%) 56.20 ± 7.41 58.56 ± 7.22 53.16 ± 8.13*## <0.001
M 53.16 ± 6.56 55.15 ± 7.62 49.60 ± 7.61 0.103
F 56.88 ± 7.45 59.40 ± 6.93 54.04 ± 8.07*## 0.001
Doctor 54.45 ± 8.13 55.84 ± 7.72 51.70 ± 4.97 0.232
Nurse 56.70 ± 7.15 59.30 ± 6.96 53.58 ± 8.83*## <0.001
LYM ratio (%) 34.77 ± 6.80 32.98 ± 6.77 39.46 ± 7.90**## <0.001
M 36.94 ± 6.22 35.92 ± 7.45 42.92 ± 8.14*# 0.015
F 34.28 ± 6.85 32.17 ± 6.46 38.61 ± 7.67**## <0.001
Doctor 35.84 ± 7.49 35.22 ± 7.61 40.45 ± 5.97 0.061
Nurse 34.46 ± 6.59 32.25 ± 6.43 39.17 ± 8.40**## <0.001
MONO ratio (%) 6.55 ± 1.43 6.49 ± 1.35 5.10 ± 0.98**## <0.001
M 6.84 ± 1.45 6.81 ± 1.67 5.27 ± 0.95**# 0.002
F 6.48 ± 1.42 6.41 ± 1.27 5.06 ± 0.99*## <0.001
Doctor 6.83 ± 1.41 6.65 ± 1.50 5.45 ± 1.08**# 0.004
Nurse 6.47 ± 1.43 6.44 ± 1.32 5.00 ± 0.94**## <0.001
EOS ratio (%) 1.89 ± 1.48 1.60 ± 1.20 1.96 ± 1.37 0.302
M 2.43 ± 1.96 1.85 ± 1.28 1.83 ± 0.76 0.358
F 1.76 ± 1.33 1.53 ± 1.18 1.86 ± 0.42 0.361
Doctor 2.29 ± 1.91 1.87 ± 1.21 1.95 ± 0.73 0.593
Nurse 1.77 ± 1.32 1.52 ± 1.19 1.83 ± 1.44 0.376
BASO ratio (%) 0.60 ± 0.29 0.47 ± 0.33 0.44 ± 0.25**↓ <0.001
M 0.63 ± 0.28 0.43 ± 0.33 0.40 ± 0.32*↓ 0.011
F 0.59 ± 0.29 0.48 ± 0.34 0.44 ± 0.26**↓ <0.001
Doctor 0.59 ± 0.27 0.46 ± 0.33 0.44 ± 0.33 0.153
Nurse 0.60 ± 0.29 0.48 ± 0.34 0.43 ± 0.23**↓ <0.001

Pre-stress = blood test data of medical workers before providing medical service for Wuhan COVID-19 patients; Post-stress = blood test data of medical workers after providing medical service for Wuhan COVID-19 patients; M = male; F = female; WBC = white blood cell; NEUT = neutrophil; LYM = lymphocyte; MONO = monocyte; EOS = eosinophil; BASO = basophilic granulocyte; NEUT = neutrophil; NLR = neutrophil-to-lymphocyte ratio; MLR = monocyte-to-lymphocyte ratio.

Continuous variables were analyzed using one-way ANOVA test. *p < 0.05, **p < 0.01 vs controls; #p < 0.05, ##p < 0.01 vs pre-press. The symbols ↑ and ↓ represented significantly higher or lower.