Fig. 3.

A) Proposed β-chitosan and quaternized ammonium chitosan derivatives preventing the SARS-CoV-2 infection by inhibiting the binding of spike protein to ACE2 receptors (recognized as primary receptor for SARS-CoV-2 binding). Alongside, interaction of ACE2 to receptor binding domain of SARS-CoV-2 has been displayed, B) Spike protein binds to the CD147 receptors, evolving as new route for virus invasion into the host cell. Chitosan oligosaccharide has been reported to downregulate the CD147 expression level which is witnessed as potential strategy for reducing the viral infection curve