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(A) Mice naive to vapor exposure were escalated on designated e-liquids in e-Vape self-administration assays using 10 daily 3-h FR1 sessions (3-s puff with 60-s timeout) (n = 4 mice/group) with the indicated commercial e-liquids. Where not indicated, nicotine is 6 mg/mL. Data are mean (± SEM) e-Vape deliveries for each session. (B) Mean inactive nose-pokes for mice during sessions described in (A).
