Figure 4.

The relationship between rs11078928 genotype and GSDMB (gasdermin-B) isoforms. The ENST identification numbers correspond to the alternatively spliced gene isoforms shown in Figure 3. The P value (Kruskal-Wallis one-way ANOVA) for the univariable relationship between genotype and transcript expression is shown at the top of each plot. Solid circles denote transcript read abundance within individuals; the boxes denote the interquartile range of transcript expression; and the middle line within each box is the median level of transcript expression. ENST = Ensembl-spiced transcript.