Table 2.
Measures of corticospinal excitability, intracortical excitability and transcallosal inhibition
| Stimulation Group Measure | Pre NL (mean ± SEM) |
Pre L (mean ± SEM) |
Post NL (mean ± SEM) |
Post L (mean ± SEM) |
|---|---|---|---|---|
| M1c | ||||
| RMT (%MSO) | 47.6±2.2 | 48.9±3.8 | 46.5±2.6 | 50.2±3.6 |
| AMT (%MSO) | 42±3.2 | 45±4.3 | 40.6±2.3 | 43.4±3.4 |
| SICI (CS+TS/TS) | 0.73±0.11 | 0.74±0.11 | 0.75±0.13 | 0.67±0.21 |
| ICF (CS+TS/TS) | 1.41±0.24 | 1.03±0.11 | 1.42±0.27 | 0.62±0.32 |
| TCI (iSPmean) | 0.67±0.04 | 0.69±0.03 | 0.71±0.04 | 0.72±0.04 |
| S1c | ||||
| RMT (%MSO) | 43.9±1.7 | 45.5±2.7 | 36.9±2.3 | 46.1±3.4 |
| AMT (%MSO) | 36.9±1.8 | 46.6±6.7 | 35.8±1.5 | 38.9±3.0 |
| SICI (CS+TS/TS) | 0.70±0.12 | 0.82±0.06 | 0.73±0.11 | 0.78±0.11 |
| ICF (CS+TS/TS) | 1.55±0.20 | 1.16±0.14 | 1.43±0.11 | 1.50±0.19 |
| TCI (iSPmean) | 0.70±0.03 | 0.70±0.02 | 0.77±0.04 | 0.74±0.03 |
| Sham | ||||
| RMT (%MSO) | 48.6±2.4 | 53.0±4.3 | 49.4±2.3 | 52.3±3.8 |
| AMT (%MSO) | 44.8±2.3 | 49.4±4.3 | 43.8±2.7 | 45.6±3.7 |
| SICI (CS+TS/TS) | 0.72±0.13 | 0.91±0.19 | 0.74±0.09 | 1.38±0.46 |
| ICF (CS+TS/TS) | 1.33±0.22 | 1.10±0.25 | 1.72±0.38 | 1.14±0.29 |
| TCI (iSPmean) | 0.69±0.04 | 0.64±0.05 | 0.76±0.03 | 0.72±0.04 |
Displayed are mean data across all stimulation groups pre and post intervention. NL = Non-lesioned hemisphere; L = Lesioned hemisphere; M1c = Contralesional primary motor cortex; S1c = Contralesional primary somatosensory cortex; Sham = Sham contralesional cTBS; RMT = Resting motor threshold; AMT = Active motor threshold; SICI = Short-interval intracortical inhibition; ICF = Intracortical facilitation; TCI = Transcallosal inhibition; %MSO = Percentage of maximum stimulator output; mV = millivolt; iSPmean = ipsilateral silent period as percentage of pre-stimulus EMG mean. Data shown are mean ± standard error of the mean (SEM).