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. 2020 Nov 16;9:9. doi: 10.12703/b/9-9

Table 1. Highly notable events in the applied rabies field related to detection, prevention, and control over the past decade.

Item Reference
Discovery of new lyssavirus species 4
Suggestion of rabies virus adaptation beyond carnivores and bats to other mammals, such as non-human primates 5
Greater appreciation of wildlife reservoirs in previously considered “rabies-free” areas 6
Recognition of additional antigen detection, serological, and molecular tests for very sensitive and specific
lyssavirus diagnosis
7
Recognizable shifts from animal culling to mass dog vaccination as a proven management strategy 8
Planning for the global elimination of human rabies mediated via dogs by 2030 9
Greater focus upon local infiltration of wounds with scarce rabies immunoglobulins 10
Availability of human monoclonal antibodies as an alternative to polyclonal rabies immunoglobulin 11
Recommendations on dose-sparing and shorter 1 week human prophylaxis regimens 12
Expansion of the distribution of vampire bats and rabies virus spread 13,197
Support for pre-exposure vaccination for those in remote settings, such as children in communities with a high
exposure rate to canine rabies virus and those at risk of vampire bat depredation
14
In vitro alternatives to animal testing in the determination of vaccine potency 15
Demonstration of compounds with repeatable in vitro anti-rabies virus activity 16
Renewal of interest for the oral vaccination of free-ranging dogs against rabies 17
Elimination of canine rabies in Mexico 18
Expectations of Gavi support for human rabies vaccination 19