Table 2. Health behaviors in individuals with milder genotypes of alpha-1 antitrypsin deficiency.

Genotype	Health behaviors	References
SZ	More likely than PiZZ to exhibit unhealthy behaviors (sedentary lifestyle, overweight, active smokers) Longer periods of smoking and higher number of packs smoked per day than PiZZ More frequent exacerbations and hospitalizations than PiZZ More visits to primary and lung physicians than PiZZ A lesser proportion of PiSZ reported to consume alcohol compared to PiZZ	5,8
MZ	Worse health behavior than PiZZ in general Worse health behavior prior to developing lung disease Broader pattern of unhealthy behavior prior to the development of lung disease (poor exercise habits, active smoking); may persist after the diagnosis Less engaged to proceed with smoking cessation-related behaviors than PiSZ or PiZZ	8
SS	Unknown relationship with lung disease Minor risk factor for developing cirrhosis only in alcohol abusers	4