Table 1. Selected proteins of the apical extracellular matrix.
| Protein family or role |
Caenorhabditis elegans |
Drosophila melanogaster | Vertebrates | References |
|---|---|---|---|---|
| Collagens | COL-182 BLI-1 |
Collagens II, V, IX, and XI |
14,23 2 |
|
| Collagen processing | TMEM-131 | 13 | ||
| Transcription factors | LIN-29 ELT-3 |
Blimp-1 Yorkie (YAP/TAZ) Ichor Ubx |
23,24 25–28 |
|
| ZP domains | FBN-1 NOAH-1 NOAH-2 |
Dumpy (Dp) Piopio (Pio) NompA Trynity (Tyn) |
α-tectorin (TECTA) β-tectorin (TECTB) |
15,16 3,12,29 30,31 |
| Nidogen + EGF | DEX-1 | α-tectorin (TECTA) |
12,19 30,31 |
|
| eLRRon | LET-4, EGG-6, SYM-1 |
Artichoke |
17 32 |
|
| Extracellular signaling pathways |
DAF-7/TGFβ DBL-1/BMP NPR-8 |
33–36 | ||
| ABC transporters + related |
Snustorr (Snu) Oskyddad (Osy) Snu-like (Snsl) |
ABCA12 |
37,38 39 |
|
| Osiris | Gore-tex (Gox) | 40 | ||
| Chitin biosynthesis/ deposition |
Obstructor-A (ObstA) Expansion (Exp) Rebuff (Reb) Apnoia (Apn) |
3,41–43 | ||
| C-type lectin | Schlaff (Slf) | 44 | ||
| Crosslinking enzymes | Alas | 26 | ||
| Proteases | Lumens interrupted (Lint) Notopleural (Np) Tracheal-prostasin (Tpr) |
27,45 | ||
| Glycoproteins | Otogelin (OTOG) Otogelin-like (OTOGL) Otoancorin Stereocilin |
30,46 |
Only selected proteins are shown owing to limitations of space.